Does Cholic Acid Interact with Fenofibric Acid?
CDI records a moderate classification for Cholic Acid and Fenofibric Acid. The stored summary is: Bile-acid binding resins may bind fenofibric acid concurrently. Administer fenofibric acid at least 1 hour before or 4-6 hours after the bile acid resin to avoid impeding absorption. The mechanism involves concurrent drug binding by bile-acid binding resins. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Cholic Acid Class
- Bile Acid
- Fenofibric Acid Class
- Peroxisome Proliferator Receptor alpha Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Concurrent drug binding by bile-acid binding resins
What To Tell Your Doctor or Pharmacist
If you are taking Cholic Acid and your doctor is considering prescribing Fenofibric Acid (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider