Factor Ix Complex Concentrates has 5 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Coagulation Factor Viia Recombinant Human, Concizumab, Emicizumab. Patients taking Factor Ix Complex Concentrates should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 4
- Moderate
- 1
Major (4)
- Factor Ix Complex Concentrates + Coagulation Factor Viia Recombinant Human— Elevated risk of serious thrombotic events when used simultaneously with FVIIa-containing products.
- Factor Ix Complex Concentrates + Concizumab— High and/or frequent doses increase risk of thromboembolism. Maximum dose of 100 units/kg within 24 hours recommended. A…
- Factor Ix Complex Concentrates + Emicizumab— Concomitant use with aPCC may result in hypercoagulability. Clinical experience suggests a drug interaction exists betwe…
- Factor Ix Complex Concentrates + Tranexamic Acid— Not recommended due to increased risk of thrombosis when used concomitantly with tranexamic acid.
Moderate (1)
- Factor Ix Complex Concentrates + Coagulation Factor X Human— Use with caution in patients receiving prothrombin complex concentrates, which may contain Factor X and could potentiate…