Pyridoxine antagonizes the action of levodopa. Should not be given concurrently unless levodopa is in a preparation containing carbidopa.
Source: NLP:pyridoxine hydrochloride
Brand names: Pyridoxine Hydrochloride
Route: Intramuscular, Intravenous
Contraindications
CONTRAINDICATIONS: A history of sensitivity to pyridoxine or to any of the ingredients in Pyridoxine Hydrochloride Injection, USP is a contraindication.
Pregnancy & Breastfeeding
Pregnancy Pregnancy Category A —The requirement for pyridoxine appears to be increased during pregnancy. Pyridoxine is sometimes of value in the treatment of nausea and vomiting of pregnancy.
2 interactions on record
Pyridoxine antagonizes the action of levodopa. Should not be given concurrently unless levodopa is in a preparation containing carbidopa.
Source: NLP:pyridoxine hydrochloride
Pyridoxine may be used concurrently with carbidopa-levodopa preparations, as carbidopa prevents pyridoxine from antagonizing levodopa.
Source: NLP:pyridoxine hydrochloride