Cefotaxime has 3 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Furosemide, Probenecid. Patients taking Cefotaxime should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Moderate
- 2
- Minor
- 1
Moderate (2)
- Cefotaxime + Furosemide— Cefotaxime may potentiate the nephrotoxic effects of furosemide. Monitor renal function when used concurrently.
- Cefotaxime + Probenecid— Probenecid decreases renal tubular transfer of cefotaxime, reducing total clearance by approximately 50% and increasing …
Minor (1)
- Cefotaxime + Alcohol— No disulfiram-like reactions were reported in a study of 22 healthy volunteers administered cefotaxime and ethanol.