Iron-Containing Preparations has 17 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acitretin, Deferasirox, Naltrexone. Patients taking Iron-Containing Preparations should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 17
- Contraindicated
- 2
- Major
- 1
- Moderate
- 14
Contraindicated (2)
- Iron-Containing Preparations + Acitretin— Acitretin interferes with the contraceptive effect of microdosed progestin-only preparations (minipills). These are not …
- Iron-Containing Preparations + Deferasirox— Do not take deferasirox with aluminum-containing antacid preparations due to potential competitive binding.
Major (1)
- Iron-Containing Preparations + Naltrexone— Naltrexone antagonizes the effects of opioid-containing antidiarrheal preparations.
Moderate (14)
- Iron-Containing Preparations + Calcitriol— Concomitant use may lead to development of hypermagnesemia. Should be used with caution or avoided.
- Iron-Containing Preparations + Demeclocycline— Absorption of tetracyclines is impaired by iron-containing preparations.
- Iron-Containing Preparations + Demeclocycline Hydrochloride— Absorption of tetracyclines is impaired by iron-containing preparations.
- Iron-Containing Preparations + Diazoxide— Diazoxide is highly bound to serum proteins and may displace bilirubin, resulting in higher blood levels of bilirubin.
- Iron-Containing Preparations + Doxycycline— Absorption of tetracyclines is impaired by iron-containing preparations.
- Iron-Containing Preparations + Doxycycline Hyclate— Iron-containing preparations impair absorption of tetracyclines.
- Iron-Containing Preparations + Interferon Gamma-1b— Simultaneous administration should be avoided due to risk of unexpected or amplified immune response.
- Iron-Containing Preparations + Minocycline Hydrochloride— Iron-containing preparations impair absorption of tetracyclines.
- Iron-Containing Preparations + Minocycline Hydrochloride Extended-Release— Absorption of tetracyclines is impaired by iron-containing preparations.
- Iron-Containing Preparations + Naltrexone Hydrochloride— Patients taking naltrexone hydrochloride may not benefit from opioid-containing cough and cold preparations.
- Iron-Containing Preparations + Omadacycline— Absorption of omadacycline is impaired by iron containing preparations.
- Iron-Containing Preparations + Risedronate Sodium— Iron preparations interfere with the absorption of risedronate sodium and should not be taken together.
- Iron-Containing Preparations + Sarecycline Hydrochloride— Coadministration may impair SEYSARA absorption and decrease efficacy. Separate dosing required.
- Iron-Containing Preparations + Tetracycline Hydrochloride— Impairs absorption of tetracyclines.