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Does Acitretin Interact with Iron Containing Preparations?

Acitretin and Iron Containing Preparations have a contraindicated drug interaction according to U.S. FDA drug labeling data. Acitretin interferes with the contraceptive effect of microdosed progestin-only preparations (minipills). These are not recommended for use with acitretin. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Acitretin Class
Retinoid
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Acitretin and your doctor is considering prescribing Iron Containing Preparations (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Acitretin(Acitretin)+💊 Iron Containing Preparations

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Retinoid
Drug B class
—
Source
NLP:acitretin

What this means in plain English

Acitretin interferes with the contraceptive effect of microdosed progestin-only preparations (minipills). These are not recommended for use with acitretin.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.