May lead to severe hypotension and deterioration in renal function, including renal failure. Monitor blood pressure and renal function; adjust dosage if needed.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide Injection 80 Mg/ 10 Ml Interactions
Brand names: Furoscix
Loop Diuretic
Route: Subcutaneous
Contraindications
4 CONTRAINDICATIONS FUROSCIX is contraindicated in: Patients with anuria Patients with a history of hypersensitivity to furosemide, any component of the FUROSCIX formulation, or medical adhesives. Anuria ( 4 ) Hypersensitivity to furosemide, components of FUROSCIX formulation, or medical adhesives. ( 4 )
13 interactions on record
Risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. Administer furosemide at lower doses with positive fluid balance and monitor renal function.
Source: NLP:furosemide injection 80 mg/ 10 ml
Risk of ototoxicity when used concomitantly with furosemide. Avoid concomitant use.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide reduces lithium's renal clearance and adds high risk of lithium toxicity. Avoid concomitant use.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Avoid combination except in life-threatening situations.
Source: NLP:furosemide injection 80 mg/ 10 ml
Potentiation occurs with furosemide. Monitor for changes in blood pressure and adjust dose of adrenergic blocking drugs if needed.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide may decrease arterial responsiveness to norepinephrine. Monitor blood pressure or mean arterial pressure.
Source: NLP:furosemide injection 80 mg/ 10 ml
May experience salicylate toxicity at lower doses because of competitive renal excretory sites. Monitor for symptoms of salicylate toxicity.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide may potentiate the action of succinylcholine. Monitor for skeletal muscle effect.
Source: NLP:furosemide injection 80 mg/ 10 ml
Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine. Monitor for skeletal muscle effect.
Source: NLP:furosemide injection 80 mg/ 10 ml
Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation.
Source: FDA drug label - furosemide injection 80 mg/ 10 ml
Intravenous administration of furosemide within 24 hours of taking chloral hydrate may cause interaction (text incomplete).
Source: NLP:furosemide injection 80 mg/ 10 ml
7.1 Effects of Furosemide on Other Drugs Drug/Substance Class or Name Drug Interaction Effect Recommendations Aminoglycoside antibiotics Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function [see Warnings and Precautions ( 5.3 )]. Cisplatin There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly [see Warnings and Precautions ( 5.3 )]. Cisplatin and nephrotoxic drugs Nephrotoxicity Administer furosemide at lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment.
Source: FDA drug label - furosemide injection 80 mg/ 10 ml