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Furosemide Injection 80 Mg/ 10 Ml

Also known as: Furoscix

Loop Diuretic

Route: Subcutaneous

Check Furosemide Injection 80 Mg/ 10 Ml Interactions →

13 interactions on record

Furosemide Injection 80 Mg/ 10 Ml has 13 known drug interactions based on U.S. FDA drug labeling data. 5 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Angiotensin Ii, Cisplatin, Ethacrynic Acid. Patients taking Furosemide Injection 80 Mg/ 10 Ml should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 13
Major: 5
Moderate: 5

Major (5)

Furosemide Injection 80 Mg/ 10 Ml + Angiotensin Ii— May lead to severe hypotension and deterioration in renal function, including renal failure. Monitor blood pressure and …
Furosemide Injection 80 Mg/ 10 Ml + Cisplatin— Risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. Administer furosemide at l…
Furosemide Injection 80 Mg/ 10 Ml + Ethacrynic Acid— Risk of ototoxicity when used concomitantly with furosemide. Avoid concomitant use.
Furosemide Injection 80 Mg/ 10 Ml + Lithium— Furosemide reduces lithium's renal clearance and adds high risk of lithium toxicity. Avoid concomitant use.
Furosemide Injection 80 Mg/ 10 Ml + Macrolide Antibiotics— Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired ren…

Moderate (5)

Furosemide Injection 80 Mg/ 10 Ml + Adrenergic Blockers— Potentiation occurs with furosemide. Monitor for changes in blood pressure and adjust dose of adrenergic blocking drugs …
Furosemide Injection 80 Mg/ 10 Ml + Norepinephrine— Furosemide may decrease arterial responsiveness to norepinephrine. Monitor blood pressure or mean arterial pressure.
Furosemide Injection 80 Mg/ 10 Ml + Salicylates— May experience salicylate toxicity at lower doses because of competitive renal excretory sites. Monitor for symptoms of …
Furosemide Injection 80 Mg/ 10 Ml + Succinylcholine— Furosemide may potentiate the action of succinylcholine. Monitor for skeletal muscle effect.
Furosemide Injection 80 Mg/ 10 Ml + Tubocurarine— Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine. Monitor for skeletal muscle…

Furosemide Injection 80 Mg/ 10 Ml + Angiotensin Ii⚠️Major

May lead to severe hypotension and deterioration in renal function, including renal failure. Monitor blood pressure and renal function; adjust dosage if needed.

Furosemide Injection 80 Mg/ 10 Ml + Cisplatin⚠️Major

Risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. Administer furosemide at lower doses with positive fluid balance and monitor renal function.

Furosemide Injection 80 Mg/ 10 Ml + Ethacrynic Acid⚠️Major

Risk of ototoxicity when used concomitantly with furosemide. Avoid concomitant use.

Furosemide Injection 80 Mg/ 10 Ml + Lithium⚠️Major

Furosemide reduces lithium's renal clearance and adds high risk of lithium toxicity. Avoid concomitant use.

Furosemide Injection 80 Mg/ 10 Ml + Macrolide Antibiotics⚠️Major

Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Avoid combination except in life-threatening situations.

Furosemide Injection 80 Mg/ 10 Ml + Adrenergic Blockers🟡Moderate

Potentiation occurs with furosemide. Monitor for changes in blood pressure and adjust dose of adrenergic blocking drugs if needed.

Furosemide Injection 80 Mg/ 10 Ml + Norepinephrine🟡Moderate

Furosemide may decrease arterial responsiveness to norepinephrine. Monitor blood pressure or mean arterial pressure.

Furosemide Injection 80 Mg/ 10 Ml + Salicylates🟡Moderate

May experience salicylate toxicity at lower doses because of competitive renal excretory sites. Monitor for symptoms of salicylate toxicity.

Furosemide Injection 80 Mg/ 10 Ml + Succinylcholine🟡Moderate

Furosemide may potentiate the action of succinylcholine. Monitor for skeletal muscle effect.

Furosemide Injection 80 Mg/ 10 Ml + Tubocurarine🟡Moderate

Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine. Monitor for skeletal muscle effect.

Furosemide Injection 80 Mg/ 10 Ml + Aldosteroneℹ️Unknown

Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation.

Furosemide Injection 80 Mg/ 10 Ml + Chloral Hydrateℹ️Unknown

Intravenous administration of furosemide within 24 hours of taking chloral hydrate may cause interaction (text incomplete).

Furosemide Injection 80 Mg/ 10 Ml + Furosemideℹ️Unknown

7.1 Effects of Furosemide on Other Drugs Drug/Substance Class or Name Drug Interaction Effect Recommendations Aminoglycoside antibiotics Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function [see Warnings and Precautions ( 5.3 )]. Cisplatin There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly [see Warnings and Precautions ( 5.3 )]. Cisplatin and nephrotoxic drugs Nephrotoxicity Administer furosemide at lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.