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Does Cisplatin Interact with Furosemide Injection 80 Mg 10 Ml?

Cisplatin and Furosemide Injection 80 Mg 10 Ml have a major drug interaction according to U.S. FDA drug labeling data. Risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. Administer furosemide at lower doses with positive fluid balance and monitor renal function. The mechanism involves ototoxicity and nephrotoxicity. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Cisplatin Class
Platinum-based Drug
Furosemide Injection 80 Mg 10 Ml Class
Loop Diuretic
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Cisplatin and Furosemide Injection 80 Mg 10 Ml occurs because ototoxicity and nephrotoxicity. Clinically, this means risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. administer furosemide at lower doses with positive fluid balance and monitor renal function. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.

What To Tell Your Doctor or Pharmacist

If you are taking Cisplatin and your doctor is considering prescribing Furosemide Injection 80 Mg 10 Ml (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Cisplatin(Cisplatin)+💊 Furosemide Injection 80 Mg 10 Ml(Furoscix)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
Platinum-based Drug
Drug B class
Loop Diuretic
Source
NLP:furosemide injection 80 mg/ 10 ml

What this means in plain English

Risk of ototoxic and nephrotoxic effects if cisplatin and furosemide are given concomitantly. Administer furosemide at lower doses with positive fluid balance and monitor renal function.

What the FDA label says

"Ototoxicity and nephrotoxicity"

📖 Source: NLP:furosemide injection 80 mg/ 10 ml

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.