Diclofenac Sodium And Menthol, Methyl Salicylate has 14 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetylsalicylic Acid, Pemetrexed, Selective Serotonin Reuptake Inhibitors (Ssri). Patients taking Diclofenac Sodium And Menthol, Methyl Salicylate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 14
- Major
- 4
- Moderate
- 10
Major (4)
- Diclofenac Sodium And Menthol, Methyl Salicylate + Acetylsalicylic Acid— Concomitant use of analgesic doses is not generally recommended due to increased risk of bleeding.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Pemetrexed— Concomitant use may increase risk of pemetrexed-associated myelosuppression, renal, and GI toxicity.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Selective Serotonin Reuptake Inhibitors (Ssri)— Concomitant use may potentiate risk of bleeding more than NSAID alone due to serotonin reuptake interference.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Warfarin— Concomitant use may increase risk of bleeding. Monitor patients for signs of bleeding.
Moderate (10)
- Diclofenac Sodium And Menthol, Methyl Salicylate + Angiotensin Ii— When administered concomitantly, patients should be adequately hydrated and renal function assessed at baseline.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Cyclosporine— Monitor for signs of worsening renal function during concomitant use.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Digoxin— Monitor serum digoxin levels during concomitant use.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Diuretics— Monitor for worsening renal function and reduced diuretic efficacy including antihypertensive effects.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Furosemide— Diuretics Clinical Impact : Clinical studies, as well as post-marketing observations, showed that NSAIDS reduced the nat…
- Diclofenac Sodium And Menthol, Methyl Salicylate + Lithium— Monitor patients for signs of lithium toxicity during concomitant use.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Mao Inhibitors— When administered concomitantly, patients should be adequately hydrated and renal function assessed at baseline.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Methotrexate— Monitor patients for methotrexate toxicity during concomitant use.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Nonselective Beta-Adrenergic Antagonists— When administered concomitantly, patients should be adequately hydrated and renal function assessed at baseline.
- Diclofenac Sodium And Menthol, Methyl Salicylate + Propranolol— NSAIDs may diminish antihypertensive effect; monitor blood pressure during concomitant use.