Digitoxin Interactions

Colestipol may reduce availability of digitoxin with conflicting study results. Particular caution required; discontinuing colestipol could be hazardous if digitoxin was titrated during colestipol use.

Source: NLP:colestipol hydrochloride

Verapamil reduces total body clearance by 27% and extrarenal clearance by 29%. Maintenance and digitalization doses should be reduced.

Source: NLP:verapamil hydrochloride

Quinidine raises serum digitoxin levels, though the effect appears smaller than with digoxin.

Source: NLP:quinidine gluconate

Potential shift in plasma concentrations due to sertraline's tight plasma protein binding, potentially resulting in adverse effects.

Source: NLP:sertraline hydrochloride

In vitro protein binding studies showed tolcapone did not displace digitoxin from binding sites at therapeutic concentrations.

Source: NLP:tolcapone