Home›Tethimide

Tethimide

3 interactions on record

Tethimide has 3 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Doxercalciferol. Patients taking Tethimide should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 3
Moderate: 1

Moderate (1)

Tethimide + Doxercalciferol— Enzyme inducer that may enhance the 25-hydroxylation of doxercalciferol. Dose adjustment of doxercalciferol may be neces…

Tethimide + Doxercalciferol🟡Moderate

Enzyme inducer that may enhance the 25-hydroxylation of doxercalciferol. Dose adjustment of doxercalciferol may be necessary.

Tethimide + Levothyroxine Sodiumℹ️Unknown

Drugs that alter thyroid hormone secretion Drugs that may decrease thyroid hormone secretion, which may result in hypothyroidism Aminoglutethimide Amiodarone Iodide (including iodine-containing Radiographic contrast agents) Lithium Methimazole Propylthioracil (PTU) Sulfonamides Tolbutamide Long-term lithium therapy can result in goiter in up to 50% of patients, and either subclinical or overt hypothyroidism, each in up to 20% of patients. Long-term amino-glu-tethimide therapy may minimally decrease T 4 and T 3 levels and increase TSH, although all values remain within normal limits in most patients.

Tethimide + Theophyllineℹ️Unknown

25% increase at allopurinol Amino glutethimide Increases theophylline clearance by induction of microsomal enzyme activity. 25% decrease Carbamazepine Similar to aminoglutethimide. 30% increase Phenobarbital (PB) Similar to aminoglutethimide.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.