Vecuronium has 8 known drug interactions based on U.S. FDA drug labeling data. 5 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Dantrolene, Dantrolene Sodium, Magnesium Sulfate Heptahydrate. Patients taking Vecuronium should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Major
- 5
- Moderate
- 3
Major (5)
- Vecuronium + Dantrolene— Dantrolene may potentiate vecuronium-induced neuromuscular blockade.
- Vecuronium + Dantrolene Sodium— Dantrolene potentiates vecuronium-induced neuromuscular blockade, which may be clinically significant.
- Vecuronium + Magnesium Sulfate Heptahydrate— Potentiation and prolongation of neuromuscular blockade is possible with concomitant use. Monitor respiration and depth …
- Vecuronium + Magnesium Sulfate In Dextrose— Potentiation and prolongation of neuromuscular blockade is possible. Magnesium suppresses peripheral neuromuscular funct…
- Vecuronium + Piperacillin And Tazobactam— Piperacillin may prolong the neuromuscular blockade of vecuronium. Monitor for adverse reactions related to neuromuscula…
Moderate (3)
- Vecuronium + Desflurane— Desflurane potentiates the effects of vecuronium. Dose adjustment may be needed during maintenance anesthesia.
- Vecuronium + Isoflurane— Isoflurane potentiates the muscle relaxant effect of vecuronium, reducing required ED95 by approximately 25-40%. Dose ad…
- Vecuronium + Sevoflurane— Sevoflurane increases both the intensity and duration of neuromuscular blockade induced by vecuronium. Dosage adjustment…