Does Magnesium Sulfate In Dextrose Interact with Vecuronium?
CDI records a major classification for Magnesium Sulfate In Dextrose and Vecuronium. The stored summary is: Potentiation and prolongation of neuromuscular blockade is possible. Magnesium suppresses peripheral neuromuscular function by decreasing acetylcholine release and reducing endplate sensitivity. The mechanism involves suppression of peripheral neuromuscular function by decreasing acetylcholine release, reduction of endplate sensitivity, and decreased muscle fiber excitability. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Suppression of peripheral neuromuscular function by decreasing acetylcholine release, reduction of endplate sensitivity, and decreased muscle fiber excitability
What To Tell Your Doctor or Pharmacist
If you are taking Magnesium Sulfate In Dextrose and your doctor is considering prescribing Vecuronium (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider