25 interactions on record
Do not use esmolol to control tachycardia in patients receiving norepinephrine due to risk of reducing cardiac contractility in presence of high systemic vascular resistance.
Source: NLP:esmolol hydrochloride
Incompatible with sodium bicarbonate solution; do not combine.
Source: NLP:sodium bicarbonate
Norepinephrine is incompatible with sodium bicarbonate solution and should not be admixed.
Source: NLP:sodium bicarbonate injection,
Concomitant use may result in severe hypertension.
Source: NLP:dopamine hydrochloride
Concomitant use may increase risk for supine hypertension due to additive blood pressure-raising effects.
Source: NLP:droxidopa
Administration to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension.
Source: NLP:marcaine, lidocaine, povidone iodine
Local anesthetic solutions containing Norepinephrine may produce severe, prolonged hypertension in patients receiving tricyclic antidepressants or monoamine oxidase inhibitors.
Source: NLP:mepivacaine hydrochloride
Concomitant use may be associated with paroxysmal hypertension and possible arrhythmia due to norepinephrine reuptake inhibition.
Source: NLP:milnacipran hydrochloride
Agonistic effects increase phenylephrine blood pressure effect.
Source: NLP:phenylephrine hydrochloride
Concomitant use may enhance the pressor response and increase the risk of hypertension.
Source: NLP:promethazine, phenylephrine, codeine
Severe, prolonged hypertension may occur with local anesthetic solutions containing norepinephrine in patients receiving monoamine oxidase inhibitors or tricyclic antidepressants.
Source: NLP:bupivacaine hydrochloride, lidocaine hydrochloride, triamcinolone acetonide, povidine iodine
Thiazides may decrease arterial responsiveness to norepinephrine, though this does not preclude therapeutic effectiveness.
Source: NLP:atenolol and chlorthalidone
May result in increased heart rates, arrhythmias, and excessive blood pressure changes when used with entacapone.
Source: NLP:carbidopa, levodopa and entacapone
Possible decreased response to norepinephrine may occur, but not sufficient to preclude its use with chlorothiazide.
Source: NLP:chlorothiazide
Possible decreased response to norepinephrine when used concurrently with chlorothiazide sodium, but not sufficient to preclude use.
Source: NLP:chlorothiazide sodium
Chlorthalidone may decrease arterial responsiveness to norepinephrine, though this does not preclude its therapeutic effectiveness as a pressor agent.
Source: NLP:chlorthalidone
Effects may be potentiated by amphetamines. Use with caution and monitor.
Source: NLP:dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate
Furosemide may decrease arterial responsiveness to norepinephrine's vasoconstricting effect.
Source: NLP:furosemide
Possible decreased response to pressor amines but not sufficient to preclude their use.
Source: NLP:hydrochlorothiazide
Indapamide may decrease arterial responsiveness to norepinephrine, though diminution is not sufficient to preclude therapeutic effectiveness as a pressor agent.
Source: NLP:indapamide
Metolazone may decrease arterial responsiveness to norepinephrine, though not sufficient to preclude therapeutic effectiveness.
Source: NLP:metolazone
Spironolactone reduces vascular responsiveness to norepinephrine; caution needed during anesthesia.
Source: NLP:spironolactone
Both spironolactone and hydrochlorothiazide reduce vascular responsiveness to norepinephrine; caution during anesthesia.
Source: NLP:spironolactone and hydrochlorothiazide
Thiazides may decrease arterial responsiveness to norepinephrine, though diminution not sufficient to preclude therapeutic effectiveness.
Source: NLP:triamterene and hydrochlorothiazide
Possible decreased response to pressor amines but not sufficient to preclude their use.
Source: NLP:amiloride hydrochloride and hydrochlorothiazide