Norepinephrine + Mepivacaine Hydrochloride Interaction

Majorinteraction on record

Description

Local anesthetic solutions containing Norepinephrine may produce severe, prolonged hypertension in patients receiving tricyclic antidepressants or monoamine oxidase inhibitors.

Mechanism

Vasopressor effect potentiation with monoamine oxidase inhibitors and tricyclic antidepressants

Source: NLP:mepivacaine hydrochloride