Does Abacavir And Lamivudine Interact with Sorbitol?
CDI records a moderate classification for Abacavir And Lamivudine and Sorbitol. The stored summary is: Coadministration may decrease lamivudine concentrations; avoid chronic coadministration of sorbitol-containing medicines with lamivudine when possible. The mechanism involves sorbitol dose-dependent reduction in lamivudine exposure. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Abacavir And Lamivudine Class
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Sorbitol dose-dependent reduction in lamivudine exposure
What To Tell Your Doctor or Pharmacist
If you are taking Abacavir And Lamivudine and your doctor is considering prescribing Sorbitol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider