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Does Acetazolamide Interact with Butalbital Aspirin Caffeine And Codeine Phosphate?

CDI records a unknown classification for Acetazolamide and Butalbital Aspirin Caffeine And Codeine Phosphate. The stored summary is: Examples: Acetazolamide, methazolamide Methotrexate Clinical Impact: Aspirin may enhance the toxicity of methotrexate by displacing it from its plasma protein binding sites and/or reducing its renal clearance. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.

Evidence status

A current label comparison is not yet available for this record. The summary and severity are stored CDI information; they have not been independently validated on this page against the exact product label.

Confirm the medicine, formulation, route, and applicable warning with your pharmacist or prescriber. Independent clinical review has not been recorded.

Stored CDI classification
Unknown
Acetazolamide Class
Carbonic Anhydrase Inhibitor
Butalbital Aspirin Caffeine And Codeine Phosphate Class
Nonsteroidal Anti-inflammatory Drug
Management
Confirm exact products with your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Acetazolamide and your doctor is considering prescribing Butalbital Aspirin Caffeine And Codeine Phosphate (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Acetazolamide+💊 Butalbital Aspirin Caffeine And Codeine Phosphate(Ascomp)

Severity & Interaction Details

ℹ️
unknown
Stored CDI classification: unknown
A current source comparison has not been recorded for this claim. The stored classification does not determine the clinical significance for your exact products or circumstances.
Severity scale
MinorContra
On record
Yes
Drug A class
Carbonic Anhydrase Inhibitor
Drug B class
Nonsteroidal Anti-inflammatory Drug
Source
FDA drug label - butalbital, aspirin, caffeine and codeine phosphate

What this means in plain English

Examples: Acetazolamide, methazolamide Methotrexate Clinical Impact: Aspirin may enhance the toxicity of methotrexate by displacing it from its plasma protein binding sites and/or reducing its renal clearance.

About Acetazolamide and Butalbital Aspirin Caffeine And Codeine Phosphate

Acetazolamide is a Carbonic Anhydrase Inhibitor, while Butalbital Aspirin Caffeine And Codeine Phosphate is a Nonsteroidal Anti-inflammatory Drug. Butalbital Aspirin Caffeine And Codeine Phosphate is also sold under the brand name Ascomp. Butalbital Aspirin Caffeine And Codeine Phosphate additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Source and Limitations

This record was produced by automated extraction from drug-label information, including AI processing. The summary and mechanism are not verbatim FDA quotations. The drug profiles below may describe different formulations from the source label. Confirm the exact product and route with your pharmacist. This page does not establish independent clinical review.

📖 Source: FDA drug label - butalbital, aspirin, caffeine and codeine phosphate

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How this information is prepared: CDI uses automated extraction, including AI, to summarize drug labeling from openFDA and includes separately identified curated-reference records. RxNorm helps identify medications; it does not verify interaction claims. Extracted summaries and CDI severity classifications can contain errors and are not verbatim FDA statements or independent clinical review. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.

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