Does Acetazolamide Interact with Chloroprocaine Hydrochloride?
CDI records a contraindicated classification for Acetazolamide and Chloroprocaine Hydrochloride. The stored summary is: Chloroprocaine should not be used when sulfonamide drugs are being employed. The para-aminobenzoic acid metabolite of chloroprocaine inhibits sulfonamide action. The mechanism involves para-aminobenzoic acid metabolite of chloroprocaine inhibits the action of sulfonamides. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Acetazolamide Class
- Carbonic Anhydrase Inhibitor
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Para-aminobenzoic acid metabolite of chloroprocaine inhibits the action of sulfonamides
What To Tell Your Doctor or Pharmacist
If you are taking Acetazolamide and your doctor is considering prescribing Chloroprocaine Hydrochloride (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider