HomeAliskiren HemifumarateAliskiren Hemifumarate + Cyclosporine

Does Aliskiren Hemifumarate Interact with Cyclosporine?

Aliskiren Hemifumarate and Cyclosporine have a contraindicated drug interaction according to U.S. FDA drug labeling data. Avoid coadministration of cyclosporine with aliskiren due to significant interaction risk. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Cyclosporine Class
Calcineurin Inhibitor Immunosuppressant
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Aliskiren Hemifumarate and your doctor is considering prescribing Cyclosporine (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Aliskiren Hemifumarate(Tekturna)+💊 Cyclosporine(Neoral)

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Calcineurin Inhibitor Immunosuppressant
Source
NLP:aliskiren hemifumarate

What this means in plain English

Avoid coadministration of cyclosporine with aliskiren due to significant interaction risk.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.