Does Aluminum Magnesium Hydroxides Interact with Tadalafil?
Aluminum Magnesium Hydroxides and Tadalafil have a minor drug interaction according to U.S. FDA drug labeling data. Simultaneous administration reduced apparent rate of tadalafil absorption without altering total exposure (AUC). The mechanism involves reduced rate of absorption. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Tadalafil Class
- Phosphodiesterase 5 Inhibitor
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Aluminum Magnesium Hydroxides and Tadalafil occurs because reduced rate of absorption. Clinically, this means simultaneous administration reduced apparent rate of tadalafil absorption without altering total exposure (auc). This is classified as a minor interaction with generally low clinical significance, though your healthcare provider should still be informed that you are taking both medications.
What To Tell Your Doctor or Pharmacist
If you are taking Aluminum Magnesium Hydroxides and your doctor is considering prescribing Tadalafil (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider