Does Amphetamine Extended Release Interact with Alkalinizing Agents?
CDI records a major classification for Amphetamine Extended Release and Alkalinizing Agents. The stored summary is: Increase blood levels and potentiate the action of amphetamine. Co-administration should be avoided. The mechanism involves alkalinizing agents increase amphetamine blood levels. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Amphetamine Extended Release Class
- Central Nervous System Stimulant
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Alkalinizing agents increase amphetamine blood levels
What To Tell Your Doctor or Pharmacist
If you are taking Amphetamine Extended Release and your doctor is considering prescribing Alkalinizing Agents (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider