Does Androgens Interact with Flotufolastat F 18?
Androgens and Flotufolastat F 18 have a unknown drug interaction according to U.S. FDA drug labeling data. Androgen receptor antagonists can result in changes in uptake of flotufolastat F-18 in prostate cancer. Effect on POSLUMA PET performance not established. The mechanism involves changes in androgen pathway affecting radiotracer uptake. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Flotufolastat F 18 Class
- Radioactive Diagnostic Agent
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Androgens and Flotufolastat F 18 occurs because changes in androgen pathway affecting radiotracer uptake. Clinically, this means androgen receptor antagonists can result in changes in uptake of flotufolastat f-18 in prostate cancer. effect on posluma pet performance not established.
What To Tell Your Doctor or Pharmacist
If you are taking Androgens and your doctor is considering prescribing Flotufolastat F 18 (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider