Angiotensin Ii + Diclofenac Sodium Topical Interaction

Moderateinteraction on record

Description

May diminish antihypertensive effect; in elderly, volume-depleted, or renal impairment patients may result in deterioration of renal function.

Mechanism

NSAIDs reduce the antihypertensive and renoprotective effects of ARBs

Source: NLP:diclofenac sodium topical