Angiotensin Ii + Irbesartan Interaction
Majorinteraction on record
Description
Dual blockade of the RAS associated with increased risks of hypotension, hyperkalemia, and changes in renal function including acute renal failure. Avoid combined use.
Mechanism
Dual blockade of the renin-angiotensin system produces additive effects and increased adverse outcomes
Source: NLP:irbesartan