Does Angiotensin Ii Interact with Lisinopril?
CDI records a major classification for Angiotensin Ii and Lisinopril. The stored summary is: Dual blockade of RAS is associated with increased risks of hypotension, hyperkalemia, and changes in renal function including acute renal failure. The mechanism involves dual blockade of the renin-angiotensin system. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Angiotensin Ii Class
- Vasoconstrictor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Dual blockade of the renin-angiotensin system
What To Tell Your Doctor or Pharmacist
If you are taking Angiotensin Ii and your doctor is considering prescribing Lisinopril (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider