Home›Azathioprine›Azathioprine + Ustekinumab Srlf

Does Azathioprine Interact with Ustekinumab Srlf?

Azathioprine and Ustekinumab Srlf have a moderate drug interaction according to U.S. FDA drug labeling data. Immunomodulator used concomitantly in approximately 30% of Crohn's disease and ulcerative colitis subjects; did not appear to influence overall safety or efficacy. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Azathioprine Class
Purine Antimetabolite
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Azathioprine and your doctor is considering prescribing Ustekinumab Srlf (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Azathioprine(Imuran)+💊 Ustekinumab Srlf(Imuldosa)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Purine Antimetabolite
Drug B class
—
Source
NLP:ustekinumab-srlf

What this means in plain English

Immunomodulator used concomitantly in approximately 30% of Crohn's disease and ulcerative colitis subjects; did not appear to influence overall safety or efficacy.

About Azathioprine and Ustekinumab Srlf

Azathioprine is a Purine Antimetabolite. You may recognize them by the brand names Imuran and Imuldosa. Azathioprine is taken by mouth, whereas Ustekinumab Srlf is given by injection under the skin. Azathioprine additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Recent research & FDA safety updates

Live

Auto-aggregated from PubMed E-utilities and FDA safety data.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Azathioprine and Ustekinumab Srlf against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.