Home›Belimumab›Belimumab + Cyclophosphamide

Does Belimumab Interact with Cyclophosphamide?

Belimumab and Cyclophosphamide have a minor drug interaction according to U.S. FDA drug labeling data. Administered concomitantly in clinical trials without evidence of clinically meaningful effect on belimumab pharmacokinetics. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Minor
Belimumab Class
B Lymphocyte Stimulator-specific Inhibitor
Cyclophosphamide Class
Alkylating Drug
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Belimumab and your doctor is considering prescribing Cyclophosphamide (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Belimumab(Benlysta)+💊 Cyclophosphamide(Frindovyx)

Severity & Interaction Details

✅
minor
Generally safe — minor interaction
Low clinical significance. Routine awareness is usually sufficient.
Severity scale
MinorContra
On record
Yes
Drug A class
B Lymphocyte Stimulator-specific Inhibitor
Drug B class
Alkylating Drug
Source
NLP:belimumab

What this means in plain English

Administered concomitantly in clinical trials without evidence of clinically meaningful effect on belimumab pharmacokinetics.

About Belimumab and Cyclophosphamide

Belimumab is a B Lymphocyte Stimulator-specific Inhibitor, while Cyclophosphamide is an Alkylating Drug. You may recognize them by the brand names Benlysta and Frindovyx. Belimumab is given by injection under the skin, whereas Cyclophosphamide is given by intravenous (IV) infusion.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Belimumab and Cyclophosphamide against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.