Bempedoic Acid And Ezetimibe + Simvastatin Interaction

Majorinteraction on record

Description

Clinically Important Drug Interactions with NEXLIZET Simvastatin Clinical Impact: Concomitant use of NEXLIZET with simvastatin causes an increase in simvastatin concentration and may increase the risk of simvastatin-related myopathy [see Clinical Pharmacology (12.3) ] . Intervention: Avoid concomitant use of NEXLIZET with simvastatin greater than 20 mg. Simvastatin: Avoid concomitant use of NEXLIZET with simvastatin greater than 20 mg.

Source: FDA drug label - bempedoic acid and ezetimibe