Does Benazepril Hydrochloride And Hydrochlorothiazide Interact with Cyclophosphamide?
Benazepril Hydrochloride And Hydrochlorothiazide and Cyclophosphamide have a unknown drug interaction according to U.S. FDA drug labeling data. Antineoplastic agents (e.g., cyclophosphamide, methotrexate): Concomitant use of thiazide diuretics may reduce renal excretion of cytotoxic agents and enhance their myelosuppressive effects. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Benazepril Hydrochloride And Hydrochlorothiazide Class
- Thiazide Diuretic
- Cyclophosphamide Class
- Alkylating Drug
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Benazepril Hydrochloride And Hydrochlorothiazide and your doctor is considering prescribing Cyclophosphamide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider