Does Bromocriptine Mesylate Interact with Acetazolamide?
CDI records a moderate classification for Bromocriptine Mesylate and Acetazolamide. The stored summary is: Bromocriptine may increase the unbound fraction of highly protein-bound sulfonamides, potentially altering their effectiveness and risk for side effects. The mechanism involves protein binding displacement. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Acetazolamide Class
- Carbonic Anhydrase Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Protein binding displacement
What To Tell Your Doctor or Pharmacist
If you are taking Bromocriptine Mesylate and your doctor is considering prescribing Acetazolamide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider