Does Calcium Acetate Interact with Ciprofloxacin?
CDI records a major classification for Calcium Acetate and Ciprofloxacin. The stored summary is: Co-administered calcium acetate decreased ciprofloxacin bioavailability by approximately 50% in a study of 15 healthy subjects. Administer ciprofloxacin at least one hour before or three hours after calcium acetate. The mechanism involves calcium binds to drugs with anionic functions. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Ciprofloxacin Class
- Fluoroquinolone Antibacterial
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Calcium binds to drugs with anionic functions
What To Tell Your Doctor or Pharmacist
If you are taking Calcium Acetate and your doctor is considering prescribing Ciprofloxacin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider