Does Carbamazepine Interact with Artemether And Lumefantrine?
CDI records a contraindicated classification for Carbamazepine and Artemether And Lumefantrine. The stored summary is: Strong CYP3A4 inducer contraindicated with artemether and lumefantrine due to potential loss of antimalarial efficacy. The mechanism involves cyp3a4 induction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Carbamazepine Class
- Mood Stabilizer
- Artemether And Lumefantrine Class
- Antimalarial
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A4 induction
What To Tell Your Doctor or Pharmacist
If you are taking Carbamazepine and your doctor is considering prescribing Artemether And Lumefantrine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider