Cedazuridine And Decitabine + Drugs Metabolized By Cyp2d6 Interaction
Majorinteraction on record
Description
Cedazuridine inhibits CDA enzyme, increasing systemic exposure and toxicity risk of CDA-metabolized drugs. Coadministration should be avoided.
Mechanism
Inhibition of cytidine deaminase (CDA) enzyme leading to increased systemic exposure
Source: NLP:cedazuridine and decitabine