Does Clindamycin Phosphate And Tretinoin Interact with Erythromycin?
CDI records a contraindicated classification for Clindamycin Phosphate And Tretinoin and Erythromycin. The stored summary is: Should not be used in combination with clindamycin phosphate and tretinoin gel due to clindamycin component. In vitro studies show antagonism between these antimicrobials. The mechanism involves antimicrobial antagonism. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Clindamycin Phosphate And Tretinoin Class
- Retinoid
- Erythromycin Class
- Macrolide
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Antimicrobial antagonism
What To Tell Your Doctor or Pharmacist
If you are taking Clindamycin Phosphate And Tretinoin and your doctor is considering prescribing Erythromycin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider