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Does Clonazepam Interact with Ritonavir 100 Mg?

Clonazepam and Ritonavir 100 Mg have a unknown drug interaction according to U.S. FDA drug labeling data. Anticonvulsants: carbamazepine, clonazepam, ethosuximide ↑ anticonvulsants A dose decrease may be needed for these drugs when co-administered with ritonavir and therapeutic concentration monitoring is recommended for these anticonvulsants, if available. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Clonazepam Class
Benzodiazepine
Ritonavir 100 Mg Class
Cytochrome P450 3A Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Clonazepam and your doctor is considering prescribing Ritonavir 100 Mg (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Clonazepam(Klonopin)+💊 Ritonavir 100 Mg(Ritonavir Film Coated)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Benzodiazepine
Drug B class
Cytochrome P450 3A Inhibitor
Source
FDA drug label - ritonavir 100 mg

What this means in plain English

Anticonvulsants: carbamazepine, clonazepam, ethosuximide ↑ anticonvulsants A dose decrease may be needed for these drugs when co-administered with ritonavir and therapeutic concentration monitoring is recommended for these anticonvulsants, if available.

About Clonazepam and Ritonavir 100 Mg

Clonazepam is a Benzodiazepine, while Ritonavir 100 Mg is a Cytochrome P450 3A Inhibitor. Clonazepam is also sold under the brand name Klonopin. Both medications are taken by mouth. Both Clonazepam and Ritonavir 100 Mg carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.