HomeCyclosporineCyclosporine + Bempedoic Acid And Ezetimibe

Does Cyclosporine Interact with Bempedoic Acid And Ezetimibe?

Cyclosporine and Bempedoic Acid And Ezetimibe have a moderate drug interaction according to U.S. FDA drug labeling data. Concomitant use increases ezetimibe and cyclosporine concentrations, with greater increases in severe renal insufficiency. Monitor cyclosporine concentrations. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Cyclosporine Class
Calcineurin Inhibitor Immunosuppressant
Bempedoic Acid And Ezetimibe Class
Adenosine Triphosphate-Citrate Lyase Inhibitor
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Cyclosporine and your doctor is considering prescribing Bempedoic Acid And Ezetimibe (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Cyclosporine(Neoral)+💊 Bempedoic Acid And Ezetimibe(Nexlizet)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Calcineurin Inhibitor Immunosuppressant
Drug B class
Adenosine Triphosphate-Citrate Lyase Inhibitor
Source
NLP:bempedoic acid and ezetimibe

What this means in plain English

Concomitant use increases ezetimibe and cyclosporine concentrations, with greater increases in severe renal insufficiency. Monitor cyclosporine concentrations.

About Cyclosporine and Bempedoic Acid And Ezetimibe

Cyclosporine is a Calcineurin Inhibitor Immunosuppressant, while Bempedoic Acid And Ezetimibe is an Adenosine Triphosphate-Citrate Lyase Inhibitor. You may recognize them by the brand names Neoral and Nexlizet. Both medications are taken by mouth. Cyclosporine additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.