Does Cyp3a Inducers Interact with Cariprazine?
CDI records a moderate classification for Cyp3a Inducers and Cariprazine. The stored summary is: Concomitant use with CYP3A4 inducers is not recommended as the net effect on cariprazine exposure is unclear and effects have not been evaluated. The mechanism involves cyp3a4 responsible for formation and elimination of cariprazine active metabolites. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Cariprazine Class
- Atypical Antipsychotic
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A4 responsible for formation and elimination of cariprazine active metabolites
What To Tell Your Doctor or Pharmacist
If you are taking Cyp3a Inducers and your doctor is considering prescribing Cariprazine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider