Cyp3a Inducers + Niraparib Tosylate Monohydrate And Abiraterone Acetate Interaction
Majorinteraction on record
Description
Strong CYP3A4 inducers may decrease abiraterone concentrations, which may reduce the effectiveness of abiraterone.
Mechanism
Abiraterone is a substrate of CYP3A4; induction decreases abiraterone concentration
Source: NLP:niraparib tosylate monohydrate and abiraterone acetate