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Does Desloratadine And Pseudoephedrine Sulfate Interact with Digitalis Glycosides?

Desloratadine And Pseudoephedrine Sulfate and Digitalis Glycosides have a moderate drug interaction according to U.S. FDA drug labeling data. Increased ectopic pacemaker activity can occur when pseudoephedrine is used with digitalis. Exercise caution when used concomitantly. The mechanism involves increased ectopic pacemaker activity. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Desloratadine And Pseudoephedrine Sulfate Class
Histamine-1 Receptor Antagonist
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Desloratadine And Pseudoephedrine Sulfate and Digitalis Glycosides occurs because increased ectopic pacemaker activity. Clinically, this means increased ectopic pacemaker activity can occur when pseudoephedrine is used with digitalis. exercise caution when used concomitantly. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.

What To Tell Your Doctor or Pharmacist

If you are taking Desloratadine And Pseudoephedrine Sulfate and your doctor is considering prescribing Digitalis Glycosides (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Desloratadine And Pseudoephedrine Sulfate(Clarinex-D 12 Hour)+💊 Digitalis Glycosides

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Histamine-1 Receptor Antagonist
Drug B class
—
Source
NLP:desloratadine and pseudoephedrine sulfate

What this means in plain English

Increased ectopic pacemaker activity can occur when pseudoephedrine is used with digitalis. Exercise caution when used concomitantly.

What the FDA label says

"Increased ectopic pacemaker activity"

📖 Source: NLP:desloratadine and pseudoephedrine sulfate

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.