Dextromethorphan + Desvenlafaxine Succinate Interaction

Moderateinteraction on record

Description

Concomitant use increases exposure (Cmax and AUC). Reduce dose by up to one-half if co-administered with 400 mg desvenlafaxine.

Mechanism

Desvenlafaxine inhibits CYP2D6 metabolism

Source: NLP:desvenlafaxine succinate