Does Empagliflozin And Linagliptin Interact with Sulfonylurea?
Empagliflozin And Linagliptin and Sulfonylurea have a major drug interaction according to U.S. FDA drug labeling data. Risk of hypoglycemia is increased when GLYXAMBI is combined with sulfonylureas (insulin secretagogues). May require lower dosages. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Major
- Empagliflozin And Linagliptin Class
- Dipeptidyl Peptidase 4 Inhibitor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Empagliflozin And Linagliptin and your doctor is considering prescribing Sulfonylurea (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider