HomeEmtricitabine Rilpivirine Hydrochloride And Tenofovir AlafenEmtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen + Lansoprazole

Does Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Interact with Lansoprazole?

Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and Lansoprazole have a contraindicated drug interaction according to U.S. FDA drug labeling data. Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole ↓ RPV Coadministration is contraindicated due to potential for loss of virologic response and development of resistance. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Lansoprazole Class
Proton Pump Inhibitor
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and your doctor is considering prescribing Lansoprazole (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen(Odefsey)+💊 Lansoprazole

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Drug B class
Proton Pump Inhibitor
Source
FDA drug label - emtricitabine, rilpivirine hydrochloride, and tenofovir alafenamide

What this means in plain English

Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole ↓ RPV Coadministration is contraindicated due to potential for loss of virologic response and development of resistance.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.