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Does Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Interact with Valacyclovir?

Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and Valacyclovir have a unknown drug interaction according to U.S. FDA drug labeling data. Some examples of drugs that are eliminated by active tubular secretion include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see Warnings and Precautions (5.5) ] . Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and your doctor is considering prescribing Valacyclovir (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen(Odefsey)+💊 Valacyclovir(Valtrex)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Drug B class
—
Source
FDA drug label - emtricitabine, rilpivirine hydrochloride, and tenofovir alafenamide

What this means in plain English

Some examples of drugs that are eliminated by active tubular secretion include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see Warnings and Precautions (5.5) ] .

About Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen and Valacyclovir

Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor. You may recognize them by the brand names Odefsey and Valtrex. Both medications are taken by mouth. Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.