Home›Ergotamine Tartrate And Caffeine›Ergotamine Tartrate And Caffeine + Propranolol

Does Ergotamine Tartrate And Caffeine Interact with Propranolol?

Ergotamine Tartrate And Caffeine and Propranolol have a major drug interaction according to U.S. FDA drug labeling data. Potentiates the vasoconstrictive action of ergotamine tartrate and caffeine by blocking the vasodilating property of epinephrine. The mechanism involves beta-blockade prevents compensatory vasodilation. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Ergotamine Tartrate And Caffeine Class
Central Nervous System Stimulant
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Ergotamine Tartrate And Caffeine and Propranolol occurs because beta-blockade prevents compensatory vasodilation. Clinically, this means potentiates the vasoconstrictive action of ergotamine tartrate and caffeine by blocking the vasodilating property of epinephrine. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.

What To Tell Your Doctor or Pharmacist

If you are taking Ergotamine Tartrate And Caffeine and your doctor is considering prescribing Propranolol (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ergotamine Tartrate And Caffeine(Cafergot)+💊 Propranolol(Hemangeol)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
Central Nervous System Stimulant
Drug B class
—
Source
NLP:ergotamine tartrate and caffeine

What this means in plain English

Potentiates the vasoconstrictive action of ergotamine tartrate and caffeine by blocking the vasodilating property of epinephrine.

About Ergotamine Tartrate And Caffeine and Propranolol

Ergotamine Tartrate And Caffeine is a Central Nervous System Stimulant. You may recognize them by the brand names Cafergot and Hemangeol. Ergotamine Tartrate And Caffeine is taken by mouth. Ergotamine Tartrate And Caffeine additionally carries an FDA boxed warning, the FDA's strongest safety alert.

What the FDA label says

"Beta-blockade prevents compensatory vasodilation"

📖 Source: NLP:ergotamine tartrate and caffeine

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Ergotamine Tartrate And Caffeine and Propranolol against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.