Erythromycin + Losartan Potassium And Hydrochlorothiazide Interaction
Unknowninteraction on record
Description
The AUC of active metabolite following oral losartan was not affected by erythromycin, another inhibitor of P450 3A4, but the AUC of losartan was increased by 30%. Ketoconazole did not affect the conversion of losartan to the active metabolite after intravenous administration of losartan, and erythromycin had no clinically significant effect after oral administration.
Source: FDA drug label - losartan potassium and hydrochlorothiazide