HomeFebuxostat Tablets 40 MgFebuxostat Tablets 40 Mg + Hydrochlorothiazide

Does Febuxostat Tablets 40 Mg Interact with Hydrochlorothiazide?

Febuxostat Tablets 40 Mg and Hydrochlorothiazide have a unknown drug interaction according to U.S. FDA drug labeling data. 7.3 In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, febuxostat does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology ( 12.3 )]. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Febuxostat Tablets 40 Mg Class
Xanthine Oxidase Inhibitor
Hydrochlorothiazide Class
Thiazide Diuretic
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Febuxostat Tablets 40 Mg and your doctor is considering prescribing Hydrochlorothiazide (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Febuxostat Tablets 40 Mg(Febuxostat)+💊 Hydrochlorothiazide

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Xanthine Oxidase Inhibitor
Drug B class
Thiazide Diuretic
Source
FDA drug label - febuxostat tablets 40 mg

What this means in plain English

7.3 In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, febuxostat does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology ( 12.3 )].

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Febuxostat Tablets 40 Mg and Hydrochlorothiazide against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.