Does Felbamate Interact with Clonazepam?
Felbamate and Clonazepam have a minor drug interaction according to U.S. FDA drug labeling data. CYP2C19 inhibitor and CYP3A4 inducer that does not affect clonazepam pharmacokinetics. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Felbamate Class
- Anti-epileptic Agent
- Clonazepam Class
- Benzodiazepine
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Felbamate and your doctor is considering prescribing Clonazepam (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider