Fluvoxamine + Olanzapine Pamoate Interaction

Moderateinteraction on record

Description

Fluvoxamine decreases olanzapine clearance, increasing olanzapine Cmax by 54-77% and AUC by 52-108%. Lower olanzapine doses should be considered.

Mechanism

CYP1A2 inhibition

Source: NLP:olanzapine pamoate