Does Fosinopril Sodium Interact with Ibuprofen?
CDI records a moderate classification for Fosinopril Sodium and Ibuprofen. The stored summary is: NSAIDs may deteriorate renal function in elderly, volume-depleted, or renally compromised patients, and may attenuate antihypertensive effect of fosinopril. Periodic renal function monitoring recommended. The mechanism involves reduced renal perfusion and antagonism of ace inhibitor effect. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Ibuprofen Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Reduced renal perfusion and antagonism of ACE inhibitor effect
What To Tell Your Doctor or Pharmacist
If you are taking Fosinopril Sodium and your doctor is considering prescribing Ibuprofen (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider