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Does Furosemide Interact with Ibuprofen And Famotidine?

Furosemide and Ibuprofen And Famotidine have a unknown drug interaction according to U.S. FDA drug labeling data. Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Furosemide Class
Loop Diuretic
Ibuprofen And Famotidine Class
Histamine-2 Receptor Antagonist
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Furosemide and your doctor is considering prescribing Ibuprofen And Famotidine (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Furosemide+💊 Ibuprofen And Famotidine(Ibuprofen And Famotidine)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Loop Diuretic
Drug B class
Histamine-2 Receptor Antagonist
Source
FDA drug label - ibuprofen and famotidine

What this means in plain English

Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients.

Recent research & FDA safety updates

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Auto-aggregated from PubMed E-utilities and FDA safety data.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.